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Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling

BACKGROUND: Despite advancements in therapies, brain metastasis in patients with triple negative subtype of breast cancer remains a therapeutic challenge. Activated microglia are often observed in close proximity to, or within, malignant tumor masses, suggesting a critical role that microglia play i...

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Detalles Bibliográficos
Autores principales: Foo, Sok Lin, Sachaphibulkij, Karishma, Lee, Corinne L. Y., Yap, Gracemary L. R., Cui, Jianzhou, Arumugam, Thiruma, Lim, Lina H. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985313/
https://www.ncbi.nlm.nih.gov/pubmed/35382852
http://dx.doi.org/10.1186/s13058-022-01514-2