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Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling
BACKGROUND: Despite advancements in therapies, brain metastasis in patients with triple negative subtype of breast cancer remains a therapeutic challenge. Activated microglia are often observed in close proximity to, or within, malignant tumor masses, suggesting a critical role that microglia play i...
Autores principales: | Foo, Sok Lin, Sachaphibulkij, Karishma, Lee, Corinne L. Y., Yap, Gracemary L. R., Cui, Jianzhou, Arumugam, Thiruma, Lim, Lina H. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985313/ https://www.ncbi.nlm.nih.gov/pubmed/35382852 http://dx.doi.org/10.1186/s13058-022-01514-2 |
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