Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis

BACKGROUND: Macular subretinal fibrosis is the end-stage complication of neovascular age-related macular degeneration (nAMD). We previously developed a mouse model of two-stage laser-induced subretinal fibrosis that mimics closely the dynamic course of macular fibrosis in nAMD patients. This study w...

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Detalles Bibliográficos
Autores principales: Yi, Caijiao, Liu, Jian, Deng, Wen, Luo, Chang, Qi, Jinyan, Chen, Mei, Xu, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985356/
https://www.ncbi.nlm.nih.gov/pubmed/35382832
http://dx.doi.org/10.1186/s12974-022-02433-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985356/
https://www.ncbi.nlm.nih.gov/pubmed/35382832
http://dx.doi.org/10.1186/s12974-022-02433-x

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