TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation

BACKGROUND: Poly(ADP-ribosyl)ation (PARylation), a posttranslational modification introduced by PARP-1 and PARP-2, has first been implicated in DNA demethylation due to its role in base excision repair. Recent evidence indicates a direct influence of PARP-dependent PARylation on TET enzymes which ca...

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Detalles Bibliográficos
Autores principales: Tolić, Anja, Ravichandran, Mirunalini, Rajić, Jovana, Đorđević, Marija, Đorđević, Miloš, Dinić, Svetlana, Grdović, Nevena, Jovanović, Jelena Arambašić, Mihailović, Mirjana, Nestorović, Nataša, Jurkowski, Tomasz P., Uskoković, Aleksandra S., Vidaković, Melita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985375/
https://www.ncbi.nlm.nih.gov/pubmed/35382873
http://dx.doi.org/10.1186/s13072-022-00445-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985375/
https://www.ncbi.nlm.nih.gov/pubmed/35382873
http://dx.doi.org/10.1186/s13072-022-00445-8

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