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Template directed synthesis of antibody Fc conjugates with concomitant ligand release

Antibodies are an attractive therapeutic modality for cancer treatment as they allow the increase of the treatment response rate and avoid the severe side effects of chemotherapy. Notwithstanding the strong benefit of antibodies, the efficacy of anti-cancer antibodies can dramatically vary among pat...

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Detalles Bibliográficos
Autores principales: Postupalenko, Viktoriia, Marx, Léo, Viertl, David, Gsponer, Nadège, Gasilova, Natalia, Denoel, Thibaut, Schaefer, Niklaus, Prior, John O., Hagens, Gerrit, Lévy, Frédéric, Garrouste, Patrick, Segura, Jean-Manuel, Nyanguile, Origène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985508/
https://www.ncbi.nlm.nih.gov/pubmed/35440989
http://dx.doi.org/10.1039/d1sc06182h