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Catalytic asymmetric synthesis of enantioenriched α-deuterated pyrrolidine derivatives
The recent promising applications of deuterium-labeled pharmaceutical compounds have led to an urgent need for the efficient synthetic methodologies that site-specifically incorporate a deuterium atom into bioactive molecules. Nevertheless, precisely building a deuterium-containing stereogenic cente...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985513/ https://www.ncbi.nlm.nih.gov/pubmed/35440992 http://dx.doi.org/10.1039/d2sc00826b |