A case of large-cell neuroendocrine carcinoma harboring rare ALK fusion with initial response to the ALK inhibitor crizotinib and acquired F1174L mutation after resistance

A 51-year-old, male, non-smoker with a 3.4 cm mass in the right middle lobe was diagnosed with large cell neuroendocrine carcinoma (LCNEC). Fluorescence in situ hybridization revealed anaplastic lymphoma kinase (ALK) gene translocation, in agreement with the immunohistochemistry result obtained with...

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Detalles Bibliográficos
Autores principales: Wang, Ye, Tian, Panwen, Wang, Weiya, Li, Yalun, Wang, Yu, Li, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985782/
https://www.ncbi.nlm.nih.gov/pubmed/35694701
http://dx.doi.org/10.1093/pcmedi/pbz005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985782/
https://www.ncbi.nlm.nih.gov/pubmed/35694701
http://dx.doi.org/10.1093/pcmedi/pbz005

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