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T790M mutation in stage IV EGFR-mutated NSCLC patient with acquired resistance reverted to original 19Del mutation after administration of a series of precision treatments: a case report

Existing studies have yet to elucidate clearly the mechanisms of secondary resistance to third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), neither is there any established standard therapy for patients resistant to third generation EGFR-TKIs. This case repor...

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Detalles Bibliográficos
Autores principales: Han, Jialong, Wang, Ya, Zhong, Lili, Zhou, Huijie, Yu, Min, Li, Yanying, Lu, You, Wang, Yan, Zhu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985812/
https://www.ncbi.nlm.nih.gov/pubmed/35692703
http://dx.doi.org/10.1093/pcmedi/pby013