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Agonists for Bitter Taste Receptors T2R10 and T2R38 Attenuate LPS-Induced Permeability of the Pulmonary Endothelium in vitro

One of the hallmarks of acute respiratory distress syndrome (ARDS) is an excessive increase in pulmonary vascular permeability. In settings of ARDS, the loss of barrier integrity is mediated by cell–cell contact disassembly and actin remodelling. Studies into molecular mechanisms responsible for imp...

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Detalles Bibliográficos
Autores principales: Kertesz, Zsuzsanna, Harrington, Elizabeth O., Braza, Julie, Guarino, Brianna D., Chichger, Havovi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985831/
https://www.ncbi.nlm.nih.gov/pubmed/35399266
http://dx.doi.org/10.3389/fphys.2022.794370