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Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells

BACKGROUND: Advances in Molecular Therapy have made gene editing through systemic or topical administration of reagents a feasible strategy to treat genetic diseases in a rational manner. Encapsulation of therapeutic agents in nanoparticles can improve intracellular delivery of therapeutic agents, p...

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Detalles Bibliográficos
Autores principales: Luks, Valerie L., Mandl, Hanna, DiRito, Jenna, Barone, Christina, Freedman-Weiss, Mollie R., Ricciardi, Adele S., Tietjen, Gregory G., Egan, Marie E., Saltzman, W. Mark, Stitelman, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986008/
https://www.ncbi.nlm.nih.gov/pubmed/35385514
http://dx.doi.org/10.1371/journal.pone.0266218