Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium

Type 2 alveolar epithelial cells (AT2s), facultative progenitor cells of the lung alveolus, play a vital role in the biology of the distal lung. In vitro model systems that incorporate human cells, recapitulate the biology of primary AT2s, and interface with the outside environment could serve as us...

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Detalles Bibliográficos
Autores principales: Abo, Kristine M., Sainz de Aja, Julio, Lindstrom-Vautrin, Jonathan, Alysandratos, Konstantinos-Dionysios, Richards, Alexsia, Garcia-de-Alba, Carolina, Huang, Jessie, Hix, Olivia T., Werder, Rhiannon B., Bullitt, Esther, Hinds, Anne, Falconer, Isaac, Villacorta-Martin, Carlos, Jaenisch, Rudolf, Kim, Carla F., Kotton, Darrell N., Wilson, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Resource and Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986076/
https://www.ncbi.nlm.nih.gov/pubmed/35315362
http://dx.doi.org/10.1172/jci.insight.155589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986076/
https://www.ncbi.nlm.nih.gov/pubmed/35315362
http://dx.doi.org/10.1172/jci.insight.155589

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