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Human antibodies against noncircumsporozoite proteins block Plasmodium falciparum parasite development in hepatocytes

Sporozoite-based approaches currently represent the most effective vaccine strategies for induction of sterile protection against Plasmodium falciparum (Pf) malaria. Clinical development of subunit vaccines is almost exclusively centered on the circum-sporozoite protein (CSP), an abundantly expresse...

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Detalles Bibliográficos
Autores principales: Fabra-García, Amanda, Yang, Annie S.P., Behet, Marije C., Yap, Zen, van Waardenburg, Youri, Kaviraj, Swarnendu, Lanke, Kjerstin, van Gemert, Geert-Jan, Jore, Matthijs M., Bousema, Teun, Sauerwein, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986077/
https://www.ncbi.nlm.nih.gov/pubmed/35167490
http://dx.doi.org/10.1172/jci.insight.153524