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Human antibodies against noncircumsporozoite proteins block Plasmodium falciparum parasite development in hepatocytes
Sporozoite-based approaches currently represent the most effective vaccine strategies for induction of sterile protection against Plasmodium falciparum (Pf) malaria. Clinical development of subunit vaccines is almost exclusively centered on the circum-sporozoite protein (CSP), an abundantly expresse...
Autores principales: | Fabra-García, Amanda, Yang, Annie S.P., Behet, Marije C., Yap, Zen, van Waardenburg, Youri, Kaviraj, Swarnendu, Lanke, Kjerstin, van Gemert, Geert-Jan, Jore, Matthijs M., Bousema, Teun, Sauerwein, Robert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986077/ https://www.ncbi.nlm.nih.gov/pubmed/35167490 http://dx.doi.org/10.1172/jci.insight.153524 |
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