Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes

BACKGROUND: Pathophysiology of type 1 diabetes (T1D) is illustrated by pancreatic islet infiltration of inflammatory lymphocytes, including CD8(+) T cells; however, the molecular factors mediating their recruitment remain unknown. We hypothesized that single-cell RNA-sequencing (scRNA-Seq) analysis...

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Detalles Bibliográficos
Autores principales: Sona, Chandan, Yeh, Yu-Te, Patsalos, Andreas, Halasz, Laszlo, Yan, Xin, Kononenko, Natalia L., Nagy, Laszlo, Poy, Matthew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986082/
https://www.ncbi.nlm.nih.gov/pubmed/35133983
http://dx.doi.org/10.1172/jci.insight.153136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986082/
https://www.ncbi.nlm.nih.gov/pubmed/35133983
http://dx.doi.org/10.1172/jci.insight.153136

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