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Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes
BACKGROUND: Pathophysiology of type 1 diabetes (T1D) is illustrated by pancreatic islet infiltration of inflammatory lymphocytes, including CD8(+) T cells; however, the molecular factors mediating their recruitment remain unknown. We hypothesized that single-cell RNA-sequencing (scRNA-Seq) analysis...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986082/ https://www.ncbi.nlm.nih.gov/pubmed/35133983 http://dx.doi.org/10.1172/jci.insight.153136 |