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SUMO-mediated recruitment allows timely function of the Yen1 nuclease in mitotic cells

The post-translational modification of DNA damage response proteins with SUMO is an important mechanism to orchestrate a timely and orderly recruitment of repair factors to damage sites. After DNA replication stress and double-strand break formation, a number of repair factors are SUMOylated and int...

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Detalles Bibliográficos
Autores principales: Dorison, Hugo, Talhaoui, Ibtissam, Mazón, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986097/
https://www.ncbi.nlm.nih.gov/pubmed/35333860
http://dx.doi.org/10.1371/journal.pgen.1009860