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SUMO-mediated recruitment allows timely function of the Yen1 nuclease in mitotic cells
The post-translational modification of DNA damage response proteins with SUMO is an important mechanism to orchestrate a timely and orderly recruitment of repair factors to damage sites. After DNA replication stress and double-strand break formation, a number of repair factors are SUMOylated and int...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986097/ https://www.ncbi.nlm.nih.gov/pubmed/35333860 http://dx.doi.org/10.1371/journal.pgen.1009860 |