CXCL12/CXCR4-Rac1–mediated migration of osteogenic precursor cells contributes to pathological new bone formation in ankylosing spondylitis

Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by inflammatory back pain and spinal ankylosis due to pathological new bone formation. Here, we identified CXCL12 as a critical contributor to pathological new bone formation through recruitment of osteogenic precursor cells...

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Detalles Bibliográficos
Autores principales: Cui, Haowen, Li, Zihao, Chen, Siwen, Li, Xiang, Chen, Dongying, Wang, Jianru, Li, Zemin, Hao, Wenjun, Zhong, Fangling, Zhang, Kuibo, Zheng, Zhaomin, Zhan, Zhongping, Liu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986111/
https://www.ncbi.nlm.nih.gov/pubmed/35385310
http://dx.doi.org/10.1126/sciadv.abl8054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986111/
https://www.ncbi.nlm.nih.gov/pubmed/35385310
http://dx.doi.org/10.1126/sciadv.abl8054

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