Cargando…
CXCL12/CXCR4-Rac1–mediated migration of osteogenic precursor cells contributes to pathological new bone formation in ankylosing spondylitis
Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by inflammatory back pain and spinal ankylosis due to pathological new bone formation. Here, we identified CXCL12 as a critical contributor to pathological new bone formation through recruitment of osteogenic precursor cells...
Autores principales: | Cui, Haowen, Li, Zihao, Chen, Siwen, Li, Xiang, Chen, Dongying, Wang, Jianru, Li, Zemin, Hao, Wenjun, Zhong, Fangling, Zhang, Kuibo, Zheng, Zhaomin, Zhan, Zhongping, Liu, Hui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986111/ https://www.ncbi.nlm.nih.gov/pubmed/35385310 http://dx.doi.org/10.1126/sciadv.abl8054 |
Ejemplares similares
-
Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis
por: Li, Xiang, et al.
Publicado: (2020) -
Tenascin-C-mediated suppression of extracellular matrix adhesion force promotes entheseal new bone formation through activation of Hippo signalling in ankylosing spondylitis
por: Li, Zihao, et al.
Publicado: (2021) -
Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection
por: Harms, Mirja, et al.
Publicado: (2023) -
Local temporal Rac1-GTP nadirs and peaks restrict cell protrusions and retractions
por: Hu, Jianjiang, et al.
Publicado: (2022) -
Activation of Piezo1 promotes osteogenic differentiation of aortic valve interstitial cell through YAP-dependent glutaminolysis
por: Zhong, Guoheng, et al.
Publicado: (2023)