Integrative molecular roadmap for direct conversion of fibroblasts into myocytes and myogenic progenitor cells

Transient MyoD overexpression in concert with small molecule treatment reprograms mouse fibroblasts into induced myogenic progenitor cells (iMPCs). However, the molecular landscape and mechanisms orchestrating this cellular conversion remain unknown. Here, we undertook an integrative multiomics appr...

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Detalles Bibliográficos
Autores principales: Kim, Inseon, Ghosh, Adhideb, Bundschuh, Nicola, Hinte, Laura, Petrosyan, Eduard, von Meyenn, Ferdinand, Bar-Nur, Ori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986113/
https://www.ncbi.nlm.nih.gov/pubmed/35385316
http://dx.doi.org/10.1126/sciadv.abj4928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986113/
https://www.ncbi.nlm.nih.gov/pubmed/35385316
http://dx.doi.org/10.1126/sciadv.abj4928

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