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ISG15 deficiency restricts HIV-1 infection

Type I interferons (IFN-Is) are a group of potent inflammatory and antiviral cytokines. They induce IFN stimulated genes (ISGs), which act as proinflammatory mediators, antiviral effectors, and negative regulators of the IFN-I signaling cascade itself. One such regulator is interferon stimulated gen...

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Detalles Bibliográficos
Autores principales: Jurczyszak, Denise, Manganaro, Lara, Buta, Sofija, Gruber, Conor, Martin-Fernandez, Marta, Taft, Justin, Patel, Roosheel S., Cipolla, Melissa, Alshammary, Hala, Mulder, Lubbertus C. F., Sachidanandam, Ravi, Bogunovic, Dusan, Simon, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986114/
https://www.ncbi.nlm.nih.gov/pubmed/35333911
http://dx.doi.org/10.1371/journal.ppat.1010405