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Effects of JZTX-V on the wild type Kv4.3 Expressed in HEK293T and Molecular Determinants in the Voltage-sensing Domains of Kv4.3 Interacting with JZTX-V

JZTX-V is a toxin isolated from the venom of the Chinese spider Chilobrachys jingzhao. Previous studies had shown that JZTX-V could inhibit the transient outward potassium current of Kv4.2 and Kv4.3 expressed in Xenopus oocytes but had no effects on Kv1.2–1.4. However, the underlying action mechanis...

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Detalles Bibliográficos
Autores principales: Dehong, Xu, Wenmei, Wu, Siqin, Hong, Peng, Zeng, Xianchun, Wang, Xiongzhi, Zeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986175/
https://www.ncbi.nlm.nih.gov/pubmed/35378047
http://dx.doi.org/10.1080/19336950.2022.2053420