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Effects of JZTX-V on the wild type Kv4.3 Expressed in HEK293T and Molecular Determinants in the Voltage-sensing Domains of Kv4.3 Interacting with JZTX-V
JZTX-V is a toxin isolated from the venom of the Chinese spider Chilobrachys jingzhao. Previous studies had shown that JZTX-V could inhibit the transient outward potassium current of Kv4.2 and Kv4.3 expressed in Xenopus oocytes but had no effects on Kv1.2–1.4. However, the underlying action mechanis...
Autores principales: | Dehong, Xu, Wenmei, Wu, Siqin, Hong, Peng, Zeng, Xianchun, Wang, Xiongzhi, Zeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986175/ https://www.ncbi.nlm.nih.gov/pubmed/35378047 http://dx.doi.org/10.1080/19336950.2022.2053420 |
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