Thioridazine Enhances Cisplatin-Induced DNA Damage in Cisplatin-Resistant Human Lung Cancer Cells

Thioridazine was used to sensitize cisplatin against cisplatin-resistant human lung cancer cells. Cells received thioridazine, cisplatin, or both drugs (the combination). Thioridazine synergized cisplatin to increase percentages of dead and apoptotic cells. DNA damage was detected using the comet as...

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Detalles Bibliográficos
Autores principales: Luo, Yuanyuan, Yu, Tinghe, Li, Xinya, Qian, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986366/
https://www.ncbi.nlm.nih.gov/pubmed/35399625
http://dx.doi.org/10.1155/2022/3702665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986366/
https://www.ncbi.nlm.nih.gov/pubmed/35399625
http://dx.doi.org/10.1155/2022/3702665

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