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Inhibition of Autophagy Facilitates XY03-EA-Mediated Neuroprotection against the Cerebral Ischemia/Reperfusion Injury in Rats

OBJECTIVE: L-3-n-Butylphthalide (NBP) is used to treat moderate and severe acute ischemia stroke. A previous screening study indicates that XY03-EA, a novel derivative of NBP, is more potent than NBP in the oxyradical scavenging capacity. In this study, in vivo and in vitro ischemia/reperfusion (I/R...

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Detalles Bibliográficos
Autores principales: Cui, Wenwen, Hao, Yuanyuan, Wang, Mingye, Zhang, Qiuyan, Wang, Junmei, Wei, Gang, Hou, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986424/
https://www.ncbi.nlm.nih.gov/pubmed/35401933
http://dx.doi.org/10.1155/2022/7013299