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Rixosomal RNA degradation contributes to silencing of Polycomb target genes
Polycomb repressive complexes 1 and 2 (PRC1 and PRC2) are histone-modifying and -binding complexes that mediate the formation of facultative heterochromatin and are required for silencing of developmental genes and maintenance of cell fate(1–3). Multiple pathways of RNA decay work together to establ...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986528/ https://www.ncbi.nlm.nih.gov/pubmed/35355014 http://dx.doi.org/10.1038/s41586-022-04598-0 |