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Rixosomal RNA degradation contributes to silencing of Polycomb target genes

Polycomb repressive complexes 1 and 2 (PRC1 and PRC2) are histone-modifying and -binding complexes that mediate the formation of facultative heterochromatin and are required for silencing of developmental genes and maintenance of cell fate(1–3). Multiple pathways of RNA decay work together to establ...

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Detalles Bibliográficos
Autores principales:	Zhou, Haining, Stein, Chad B., Shafiq, Tiasha A., Shipkovenska, Gergana, Kalocsay, Marian, Paulo, Joao A., Zhang, Jiuchun, Luo, Zhenhua, Gygi, Steven P., Adelman, Karen, Moazed, Danesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986528/ https://www.ncbi.nlm.nih.gov/pubmed/35355014 http://dx.doi.org/10.1038/s41586-022-04598-0

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