Intercellular Propagation and Aggregate Seeding of Mutant Ataxin-1

Intercellular propagation of aggregated protein inclusions along actin-based tunneling nanotubes (TNTs) has been reported as a means of pathogenic spread in Alzheimer’s, Parkinson’s, and Huntington’s diseases. Propagation of oligomeric-structured polyglutamine-expanded ataxin-1 (Atxn1[154Q]) has bee...

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Detalles Bibliográficos
Autores principales: Huang, Haoyang, Toker, Nicholas, Burr, Eliza, Okoro, Jeff, Moog, Maia, Hearing, Casey, Lagalwar, Sarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986690/
https://www.ncbi.nlm.nih.gov/pubmed/34826062
http://dx.doi.org/10.1007/s12031-021-01944-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986690/
https://www.ncbi.nlm.nih.gov/pubmed/34826062
http://dx.doi.org/10.1007/s12031-021-01944-1

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