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Glutathione S-transferase Mu 2 inhibits hepatic steatosis via ASK1 suppression

Hepatic steatosis is the main characteristic of some liver metabolism diseases. However, unclear molecular mechanism of hepatic steatosis impedes the therapy of this hepatic steatosis. Glutathione-S-transferase mu 2 (GSTM2), as a member of phase II drug metabolizing enzymes (DMEs), regulates cellula...

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Detalles Bibliográficos
Autores principales: Jin, Yi, Tan, Yanjie, Zhao, Pengxiang, Guo, Yu, Chen, Shilin, Wu, Jian, Ren, Zhuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986781/
https://www.ncbi.nlm.nih.gov/pubmed/35388144
http://dx.doi.org/10.1038/s42003-022-03251-w