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scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation

DNA methylation is a central epigenetic mark that has diverse roles in gene regulation, development, and maintenance of genome integrity. 5 methyl cytosine (5mC) can be interrogated at base resolution in single cells by using bisulfite sequencing (scWGBS). Several different scWGBS strategies have be...

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Detalles Bibliográficos
Autores principales: Raine, Amanda, Lundmark, Anders, Annett, Alva, Wiman, Ann-Christin, Cavalli, Marco, Wadelius, Claes, Bergin, Claudia, Nordlund, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986790/
https://www.ncbi.nlm.nih.gov/pubmed/35388090
http://dx.doi.org/10.1038/s41598-022-09798-2