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DNA sequence-dependent formation of heterochromatin nanodomains

The mammalian epigenome contains thousands of heterochromatin nanodomains (HNDs) marked by di- and trimethylation of histone H3 at lysine 9 (H3K9me2/3), which have a typical size of 3–10 nucleosomes. However, what governs HND location and extension is only partly understood. Here, we address this is...

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Detalles Bibliográficos
Autores principales: Thorn, Graeme J., Clarkson, Christopher T., Rademacher, Anne, Mamayusupova, Hulkar, Schotta, Gunnar, Rippe, Karsten, Teif, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986797/
https://www.ncbi.nlm.nih.gov/pubmed/35387992
http://dx.doi.org/10.1038/s41467-022-29360-y