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Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation
3-phosphoinositide-dependent kinase 1 (PDK1) is an essential serine/threonine protein kinase, which plays a crucial role in cell growth and proliferation. It is often referred to as a ‘master’ kinase due to its ability to activate at least 23 downstream protein kinases implicated in various signalin...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986801/ https://www.ncbi.nlm.nih.gov/pubmed/35387990 http://dx.doi.org/10.1038/s41467-022-29368-4 |