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scTEM-seq: Single-cell analysis of transposable element methylation to link global epigenetic heterogeneity with transcriptional programs

Global changes in DNA methylation are observed in development and disease, and single-cell analyses are highlighting the heterogeneous regulation of these processes. However, technical challenges associated with single-cell analysis of DNA methylation limit these studies. We present single-cell tran...

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Detalles Bibliográficos
Autores principales: Hunt, Kooper V., Burnard, Sean M., Roper, Ellise A., Bond, Danielle R., Dun, Matthew D., Verrills, Nicole M., Enjeti, Anoop K., Lee, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986802/
https://www.ncbi.nlm.nih.gov/pubmed/35388081
http://dx.doi.org/10.1038/s41598-022-09765-x