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Ribonuclease-1 treatment after traumatic brain injury preserves blood–brain barrier integrity and delays secondary brain damage in mice

Traumatic brain injury (TBI) involves primary mechanical damage and delayed secondary damage caused by vascular dysfunction and neuroinflammation. Intracellular components released into the parenchyma and systemic circulation, termed danger-associated molecular patterns (DAMPs), are major drivers of...

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Detalles Bibliográficos
Autores principales: Krämer, Tobias J., Hübener, Per, Pöttker, Bruno, Gölz, Christina, Neulen, Axel, Pantel, Tobias, Goetz, Hermann, Ritter, Katharina, Schäfer, Michael K. E., Thal, Serge C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986812/
https://www.ncbi.nlm.nih.gov/pubmed/35388024
http://dx.doi.org/10.1038/s41598-022-09326-2