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Ribonuclease-1 treatment after traumatic brain injury preserves blood–brain barrier integrity and delays secondary brain damage in mice
Traumatic brain injury (TBI) involves primary mechanical damage and delayed secondary damage caused by vascular dysfunction and neuroinflammation. Intracellular components released into the parenchyma and systemic circulation, termed danger-associated molecular patterns (DAMPs), are major drivers of...
Autores principales: | Krämer, Tobias J., Hübener, Per, Pöttker, Bruno, Gölz, Christina, Neulen, Axel, Pantel, Tobias, Goetz, Hermann, Ritter, Katharina, Schäfer, Michael K. E., Thal, Serge C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986812/ https://www.ncbi.nlm.nih.gov/pubmed/35388024 http://dx.doi.org/10.1038/s41598-022-09326-2 |
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