Mitochondria bridge HIF signaling and ferroptosis blockage in acute kidney injury

Ferroptosis, a form of regulated cell death, plays an important role in acute kidney injury (AKI). Previous studies have shown that prolyl hydroxylase domain protein (PHD) inhibitors that activate HIF signaling provide strong protection against AKI, which is characterized by marked cell death. Howev...

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Detalles Bibliográficos
Autores principales: Li, Wenju, Xiang, Zhidan, Xing, Yuexian, Li, Shen, Shi, Shaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986825/
https://www.ncbi.nlm.nih.gov/pubmed/35387983
http://dx.doi.org/10.1038/s41419-022-04770-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986825/
https://www.ncbi.nlm.nih.gov/pubmed/35387983
http://dx.doi.org/10.1038/s41419-022-04770-4

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