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Mitochondria bridge HIF signaling and ferroptosis blockage in acute kidney injury
Ferroptosis, a form of regulated cell death, plays an important role in acute kidney injury (AKI). Previous studies have shown that prolyl hydroxylase domain protein (PHD) inhibitors that activate HIF signaling provide strong protection against AKI, which is characterized by marked cell death. Howev...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986825/ https://www.ncbi.nlm.nih.gov/pubmed/35387983 http://dx.doi.org/10.1038/s41419-022-04770-4 |