Cargando…

Melatonin reduces the endoplasmic reticulum stress and polyubiquitinated protein accumulation induced by repeated anesthesia exposure in Caenorhabditis elegans

Endoplasmic reticulum (ER) stress has been linked to anesthesia-induced neurotoxicity, but melatonin seems to play a protective role against ER stress. Synchronized Caenorhabditis elegans were exposed to isoflurane during the developmental period; melatonin treatment was used to evaluate its role in...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Hyun-Jung, Koo, Bon-Wook, Yoon, Jiwon, Kim, Heeyeon, Do, Sang-Hwan, Na, Hyo-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986834/
https://www.ncbi.nlm.nih.gov/pubmed/35388108
http://dx.doi.org/10.1038/s41598-022-09853-y