Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing

Circulating tumor DNA (ctDNA) analysis has emerged as a clinically useful tool for cancer diagnostics and treatment monitoring. However, ctDNA detection is complicated by low DNA concentrations and technical challenges. Here we describe our newly developed sensitive method for ctDNA detection on the...

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Detalles Bibliográficos
Autores principales: Tjensvoll, Kjersti, Lapin, Morten, Gilje, Bjørnar, Garresori, Herish, Oltedal, Satu, Forthun, Rakel Brendsdal, Molven, Anders, Rozenholc, Yves, Nordgård, Oddmund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986848/
https://www.ncbi.nlm.nih.gov/pubmed/35388068
http://dx.doi.org/10.1038/s41598-022-09698-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986848/
https://www.ncbi.nlm.nih.gov/pubmed/35388068
http://dx.doi.org/10.1038/s41598-022-09698-5

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