Characterization of Cme and Yme thermostable Cas12a orthologs

CRISPR-Cas12a proteins are RNA-guided endonucleases that cleave invading DNA containing target sequences adjacent to protospacer adjacent motifs (PAM). Cas12a orthologs have been repurposed for genome editing in non-native organisms by reprogramming them with guide RNAs to target specific sites in g...

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Detalles Bibliográficos
Autores principales: Fuchs, Ryan T., Curcuru, Jennifer L., Mabuchi, Megumu, Noireterre, Audrey, Weigele, Peter R., Sun, Zhiyi, Robb, G. Brett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986864/
https://www.ncbi.nlm.nih.gov/pubmed/35388146
http://dx.doi.org/10.1038/s42003-022-03275-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986864/
https://www.ncbi.nlm.nih.gov/pubmed/35388146
http://dx.doi.org/10.1038/s42003-022-03275-2

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