HspBP1 is a dual function regulatory protein that controls both DNA repair and apoptosis in breast cancer cells

The Hsp70-binding protein 1 (HspBP1) belongs to a family of co-chaperones that regulate Hsp70 activity and whose biological significance is not well understood. In the present study, we show that when HspBP1 is either knocked down or overexpressed in BRCA1-proficient breast cancer cells, there were...

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Detalles Bibliográficos
Autores principales: Youn, Cha Kyung, Lee, Jung-Hee, Hariharasudhan, Gurusamy, Kim, Hong Beum, Kim, Jeeho, Lee, Sumi, Lim, Sung-Chul, Yoon, Sang-Pil, Park, Sang-Gon, Chang, In-Youb, You, Ho Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986865/
https://www.ncbi.nlm.nih.gov/pubmed/35387978
http://dx.doi.org/10.1038/s41419-022-04766-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986865/
https://www.ncbi.nlm.nih.gov/pubmed/35387978
http://dx.doi.org/10.1038/s41419-022-04766-0

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