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Neonatal encephalopathy plasma metabolites are associated with neurodevelopmental outcomes

BACKGROUND: To investigate mechanisms of injury and recovery in neonatal encephalopathy (NE), we performed targeted metabolomic analysis of plasma using LC/MS/MS from healthy term neonates or neonates with NE. METHODS: Plasma samples from the NE (n=45, day of life 0–1) or healthy neonatal (n=30, ≥36...

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Detalles Bibliográficos
Autores principales: Friedes, Barbara D., Molloy, Eleanor, Strickland, Tammy, Zhu, Jie, Slevin, Marie, Donoghue, Veronica, Sweetman, Deirdre, Kelly, Lynne, O’Dea, Mary, Roux, Aurelie, Harlan, Robert, Ellis, Gregory, Manlhiot, Cedric, Graham, David, Northington, Frances, Everett, Allen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986879/
https://www.ncbi.nlm.nih.gov/pubmed/34621028
http://dx.doi.org/10.1038/s41390-021-01741-x