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Novel [(18)F]-labeled thiol for the labeling of Dha- or maleimide-containing biomolecules
BACKGROUND: Prosthetic approach for the radiolabeling of biologics with fluorine-18 is a robust strategy and has been employed for many years. It requires fast, biocompatible and selective reactions suited to these fragile molecules. Michael addition of a nucleophilic thiol moiety on α,β-unsaturated...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986957/ https://www.ncbi.nlm.nih.gov/pubmed/35384570 http://dx.doi.org/10.1186/s41181-022-00160-5 |