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Novel [(18)F]-labeled thiol for the labeling of Dha- or maleimide-containing biomolecules

BACKGROUND: Prosthetic approach for the radiolabeling of biologics with fluorine-18 is a robust strategy and has been employed for many years. It requires fast, biocompatible and selective reactions suited to these fragile molecules. Michael addition of a nucleophilic thiol moiety on α,β-unsaturated...

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Detalles Bibliográficos
Autores principales: Richard, Mylène, Hinnen, Françoise, Kuhnast, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986957/
https://www.ncbi.nlm.nih.gov/pubmed/35384570
http://dx.doi.org/10.1186/s41181-022-00160-5