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Sulforaphane Attenuates Chronic Intermittent Hypoxia-Induced Brain Damage in Mice via Augmenting Nrf2 Nuclear Translocation and Autophagy

Obstructive sleep apnea–hypopnea syndrome (OSAHS), typically characterized by chronic intermittent hypoxia (CIH), is associated with neurocognitive dysfunction in children. Sulforaphane (SFN), an activator of nuclear factor E2-related factor 2 (Nrf2), has been demonstrated to protect against oxidati...

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Detalles Bibliográficos
Autores principales: Li, Xiucui, Ying, Huiya, Zhang, Zilong, Yang, Zijing, You, Cancan, Cai, Xiaohong, Lin, Zhongdong, Xiao, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8986999/
https://www.ncbi.nlm.nih.gov/pubmed/35401114
http://dx.doi.org/10.3389/fncel.2022.827527