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Targeted Codelivery of Prodigiosin and Simvastatin Using Smart BioMOF: Functionalization by Recombinant Anti-VEGFR1 scFv

Biological metal-organic frameworks (BioMOFs) are hybrid compounds in which metal nodes are linked to biocompatible organic ligands and have potential for medical application. Herein, we developed a novel BioMOF modified with an anti-VEGFR1 scFv antibody (D16F7 scFv). Our BioMOF is co-loaded with a...

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Detalles Bibliográficos
Autores principales: Mirzaeinia, Somayyeh, Zeinali, Sedighe, Budisa, Nediljko, Karbalaei-Heidari, Hamid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987009/
https://www.ncbi.nlm.nih.gov/pubmed/35402395
http://dx.doi.org/10.3389/fbioe.2022.866275