Low molecular weight polysialic acid binds to properdin and reduces the activity of the alternative complement pathway

Sialic acids as the terminal caps of the cellular glycocalyx play an essential role in self-recognition and were shown to modulate complement processes via interaction between α2,3-linked sialic acids and complement factor H. Previously, it was suggested that low molecular weight α2,8-linked polysia...

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Detalles Bibliográficos
Autores principales: Shahraz, Anahita, Lin, Yuchen, Mbroh, Joshua, Winkler, Jonas, Liao, Huan, Lackmann, Marie, Bungartz, Annemarie, Zipfel, Peter F., Skerka, Christine, Neumann, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987038/
https://www.ncbi.nlm.nih.gov/pubmed/35388026
http://dx.doi.org/10.1038/s41598-022-09407-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987038/
https://www.ncbi.nlm.nih.gov/pubmed/35388026
http://dx.doi.org/10.1038/s41598-022-09407-2

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