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Low molecular weight polysialic acid binds to properdin and reduces the activity of the alternative complement pathway
Sialic acids as the terminal caps of the cellular glycocalyx play an essential role in self-recognition and were shown to modulate complement processes via interaction between α2,3-linked sialic acids and complement factor H. Previously, it was suggested that low molecular weight α2,8-linked polysia...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987038/ https://www.ncbi.nlm.nih.gov/pubmed/35388026 http://dx.doi.org/10.1038/s41598-022-09407-2 |