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SIX5-activated LINC01468 promotes lung adenocarcinoma progression by recruiting SERBP1 to regulate SERPINE1 mRNA stability and recruiting USP5 to facilitate PAI1 protein deubiquitylation

Increasing research has uncovered the involvement of long noncoding RNAs (lncRNAs) in the progression of multiple cancers including lung adenocarcinoma (LUAD). RT-qPCR and western blot were done to measure RNAs and proteins. Functional assays assessed LUAD cell biological behaviors under knockdown o...

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Detalles Bibliográficos
Autores principales: Yuan, Yuan, Zhou, Danyang, Chen, Feifei, Yang, Zhenhua, Gu, Wei, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987051/
https://www.ncbi.nlm.nih.gov/pubmed/35387981
http://dx.doi.org/10.1038/s41419-022-04717-9