Prolonged treatment with the proteasome inhibitor MG-132 induces apoptosis in PC12 rat pheochromocytoma cells

Rat pheochromocytoma (PC12) cells were treated with the proteasome inhibitor MG-132 and morphological changes were recorded. Initially, neuronal differentiation was induced but after 24 h signs of morphological deterioration became apparent. We performed nuclear staining, flow cytometry and WST-1 as...

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Detalles Bibliográficos
Autores principales: Tarjányi, Oktávia, Haerer, Julian, Vecsernyés, Mónika, Berta, Gergely, Stayer-Harci, Alexandra, Balogh, Bálint, Farkas, Kornélia, Boldizsár, Ferenc, Szeberényi, József, Sétáló, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987075/
https://www.ncbi.nlm.nih.gov/pubmed/35388084
http://dx.doi.org/10.1038/s41598-022-09763-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987075/
https://www.ncbi.nlm.nih.gov/pubmed/35388084
http://dx.doi.org/10.1038/s41598-022-09763-z

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