Macrophage-derived IGF-1 protects the neonatal intestine against necrotizing enterocolitis by promoting microvascular development

Necrotizing enterocolitis (NEC) is a deadly bowel necrotic disease of premature infants. Low levels of plasma IGF-1 predispose premature infants to NEC. While increasing evidence suggests that defective perinatal intestinal microvascular development plays a role in NEC, the involved mechanism remain...

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Detalles Bibliográficos
Autores principales: Yan, Xiaocai, Managlia, Elizabeth, Zhao, You-Yang, Tan, Xiao-Di, De Plaen, Isabelle G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987083/
https://www.ncbi.nlm.nih.gov/pubmed/35388142
http://dx.doi.org/10.1038/s42003-022-03252-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987083/
https://www.ncbi.nlm.nih.gov/pubmed/35388142
http://dx.doi.org/10.1038/s42003-022-03252-9

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