CRISPR-mediated multiplexed live cell imaging of nonrepetitive genomic loci with one guide RNA per locus

Three-dimensional (3D) structures of the genome are dynamic, heterogeneous and functionally important. Live cell imaging has become the leading method for chromatin dynamics tracking. However, existing CRISPR- and TALE-based genomic labeling techniques have been hampered by laborious protocols and a...

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Detalles Bibliográficos
Autores principales: Clow, Patricia A., Du, Menghan, Jillette, Nathaniel, Taghbalout, Aziz, Zhu, Jacqueline J., Cheng, Albert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987088/
https://www.ncbi.nlm.nih.gov/pubmed/35387989
http://dx.doi.org/10.1038/s41467-022-29343-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987088/
https://www.ncbi.nlm.nih.gov/pubmed/35387989
http://dx.doi.org/10.1038/s41467-022-29343-z

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